Isaac Yiadom grew up Worcester, MA while he attended Doherty Memorial. There he was recruited by Boston College and was ranked the #3 recruit in Massachusetts by ESPN.

As a Freshman, he saw time in all 13 games and completed 127 plays on special teams.

During his sophomore season, he had a game high six tackles against Florida State and started 7 out of 9 games. He played in all 13 games his junior year and made 8 starts at left corner.

Isaac then became a leader of the defensive unit at Boston College during his senior year and was invited to the Reese’s Senior Bowl after declaring for the NFL Draft. He also received the Jay McGillis Memorial Scholarship Award his Senior season.

Isaac found a 2nd home in the weight room, earning him the nickname "Ike Diesel". Yiadom was drafted by the Denver Broncos in the third round, 99th overall, of the 2018 NFL Draft.